Take this WebMD quiz and find out if you know the facts about genital herpes. Genital herpes is caused by the herpes simplex virus (HSV) type 1 or type 2. It causes painful blisters to appear on the genitals and the surrounding areas. The strongest predictor for infection is a person's number of lifetime sex partners. The natural history includes first- episode mucocutaneous infection, establishment of latency in the dorsal root ganglion, and subsequent reactivation. Most infections are transmitted via asymptomatic viral shedding. Classic outbreaks consist of a skin prodrome and possible constitutional symptoms such as headache, fever, and inguinal lymphadenopathy. As the infection progresses, papules, vesicles on an erythematous base, and erosions appear over hours to days. These lesions usually crust, re- epithelialize, and heal without scarring. First- episode infections are more extensive: primary lesions last two to six weeks versus approximately one week for lesions in recurrent disease. Atypical manifestations are common.
Infected persons experience a median of four recurrences per year after their first episode, but rates vary greatly. Genital herpes simplex virus type 2 recurs six times more frequently than type 1. Viral culture is preferred over polymerase chain reaction testing for diagnosis. Serologic testing can be useful in persons with a questionable history. Effective oral antiviral medications are available for initial, episodic, and suppressive therapy but are not a cure. There is some evidence that alternative therapies such as L- lysine, zinc, and some herbal preparations may offer some benefit. Counseling patients about the risk of transmission is crucial and helps prevent the spread of disease and neonatal complications. Louis: Mosby, 1. 99. Genital herpes simplex virus infection is a recurrent, lifelong disease with no cure. The strongest predictor for infection is a person's number of. Genital herpes information. Learn about genital herpes symptoms and treatments. Type- specific antibodies for diagnosis and management. Long- term recurrence rates of genital herpes infections after treatment of first- episode genital herpes with oral acyclovir. In: Kono R, Nakajima A. Herpes viruses and virus chemotherapy: pharmacological and clinical approaches: proceedings of the International Symposium on Pharmacological and Clinical Approaches to Herpes Viruses and Virus Chemotherapy, Oiso, Japan, 1. September 1. 98. 4. Amsterdam and New York: Elsevier, 1. Collaborative Famciclovir Genital Herpes Research Group. International Valaciclovir HSV Study Group. Acyclovir Study Group. Treatment and prophylaxis. Kimberlin, M.D., and Dwight J. N Engl J Med 2004; 350:1970-1977 May 6, 2004 DOI: 10.1056. I am just beginning a relationship with a new partner. He has revealed to me that he has HSV2 (genital), but is asymptomatic and has never had an outbreak. Genital herpes — Comprehensive overview covers symptoms, treatment of this highly contagious disease. Genital Herpes Clinical Trials 2016
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